The birth and postnatal development of purinergic signalling.

نویسندگان

  • G Burnstock
  • B B Fredholm
  • R A North
  • A Verkhratsky
چکیده

The purinergic signalling system is one of the most ancient and arguably the most widespread intercellular signalling system in living tissues. In this review we present a detailed account of the early developments and current status of purinergic signalling. We summarize the current knowledge on purinoceptors, their distribution and role in signal transduction in various tissues in physiological and pathophysiological conditions.

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عنوان ژورنال:
  • Acta physiologica

دوره 199 2  شماره 

صفحات  -

تاریخ انتشار 2010